Table 1.
Inflammation and cancer have distinct cytokine profiles. Cytokines can be grouped according to expression profile. Cytokines associated with inflammation are significantly increased in inflamed prostates, regardless of cancer status. Cytokines associated with cancer are significantly increased in cancer, regardless of inflammation status. Concurrent inflammation and cancer cytokines are significantly increased only when inflammation and cancer are simultaneous
| Cytokines associated with inflammation
|
Cytokines associated with cancer
|
|||
|---|---|---|---|---|
| Inflammation only | Augmented by cancer | Cancer only | Augmented by inflammation | Concurrent inflammation and cancer only |
| CCL3 | IL-1a IL-2 | IL-5 | CXCL10 | IL-4 CXCL1 |
| FGF | IL-1b IL-17 | IL-13 | IL-6 CXCL9 | |
| TNFα | CCL2 | IL-12 IFNγ | ||