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. Author manuscript; available in PMC: 2015 Mar 7.
Published in final edited form as: Cardiovasc Intervent Radiol. 2010 Nov 12;34(1):37–49. doi: 10.1007/s00270-010-0012-y

Table 2.

Periprocedural complications and reported toxicities in DEB-TACE studies of patients with unresectable HCC

Study No. of patients Complications PES Toxicities
Varela et al. [9] 27

  • Liver abscess (2/27)

  • Liver failure (1/27)

  • Hepatic artery dissection (1/27)

 NA

  • Transient increase in AST and bilirubin
Reyes et al. [23] 20

  • Tumor rupture (1/20)

  • Pancreatitis (1/20)

 1/20

  • Leukocytopenia grade 3 (1/20)
Poon et al. [50] 35

  • Tumor rupture

  • Liver failure

  • Pleural effusion

  • Gastric ulcer bleeding, esophageal variceal bleeding

  • Spontaneous bacterial peritonitis

 27/35

  • None, transient increase in bilirubin, AST, ALT, and WBC
Grosso et al. [74] 50

  • Pancreatitis

 9/50

  • Transient increase in AST, ALT, GTT
Malagari et al. [21] 62

  • Cholecystitis (1/62)

  • Liver abscess (1/62)

 62/62

  • Transient increase in AST, ALT, GTT
Forner et al. [19] 27

  • Arterial dissection (1/27)

  • Liver abscess (1/27)

 NA

  • NA
Lammer et al.— PRECISION V [20] 212 (102 DEB)

  • Liver failure

  • GI bleeding

  • Infection

 NA

  • Alopecia (1.1%)

  • Marrow suppression (5.4%)

  • Mucositis (4.3%)

  • Skin discoloration (2.2%)

NA not applicable, AST aspartate aminotransferase, ALT alanine aminotransferase, GTT glucose tolerance test, WBC white blood cell count