Table 5.
Adjusted regression modelsa for subset analyses of prenatal antibiotic use as a predictor of asthma and wheezing
Asthma by Year 3 | Wheezing in Year 3 | |||
---|---|---|---|---|
OR [95% CI] | P-Value | OR [95% CI] | P-Value | |
No Maternal Asthma (n=200) | 5.75 [1.78, 18.60] | 0.004 | 1.50 [0.65, 3.46] | 0.34 |
No First Year Antibiotics (n=137) | 3.62 [1.09, 12.05] | 0.036 | 1.61 [0.60, 4.31] | 0.35 |
Adjusted analysis includes study intervention as well as significant variables (p<0.10) from univariate analysis. Asthma is adjusted for study intervention, Mexican ancestry, smoking during pregnancy, ibuprofen during pregnancy, mother having asthma, exposure to smoke in the home in the first year of life, and child antibiotic use for respiratory reasons. Wheezing is adjusted for study intervention, Mexican ancestry, smoking during pregnancy, ibuprofen during pregnancy, mother having asthma, low birth weight, any breast feeding, exposure to smoke in the home in the first year of life, and child antibiotic use for respiratory reasons.