Table 2.
GABAA receptor modulators and oral contraceptives interact to promote euthymia.
| 2A. GABAA receptor modulators not including lamotrigine | ||||||
|---|---|---|---|---|---|---|
| GABA− OCP− | GABA− OCP+ | GABA+ OCP− | GABA+ OCP+ | F(1,1) | p | |
| Mean mood overall | 49.4 | 46.6 | 43.9 | 50.4 | 7.854 | 0.006 |
| Mean follicular mood | 50.1 | 47.0 | 44.6 | 51.0 | 9.591 | 0.003 |
| Mean luteal mood | 48.6 | 46.9 | 43.1 | 49.8 | 4.640 | 0.034 |
| Mean flow mood | 48.4 | 45.9 | 42.9 | 48.8 | 4.475 | 0.037 |
| 2B. GABAA receptor modulators + lamotrigine | ||||||
|---|---|---|---|---|---|---|
| GABA− OCP− | GABA− OCP+ | GABA+ OCP− | GABA+ OCP+ | F(1,1) | p | |
| Mean mood overall | 51.2 | 41.2 | 45.6 | 50.4 | 9.344 | 0.003 |
| Mean follicular mood | 52.1 | 44.0 | 46.3 | 50.8 | 10.182 | 0.002 |
| Mean luteal mood | 51.8 | 43.0 | 44.4 | 50.0 | 8.546 | 0.004 |
| Mean flow mood | 50.8 | 41.3 | 44.4 | 49.1 | 7.946 | 0.006 |