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. 2015 Jan 5;2015:902821. doi: 10.1155/2015/902821

Table 2.

Qualitative and quantitative agreements between anti-dsDNA antibody assays.

  NOVA Lite  
dsDNA CLIFT		 QUANTA Flash 
dsDNA		 QUANTA Lite  
dsDNA SC		 BioPlex 2200 
dsDNA		 ImmuLisa 
dsDNA
QUANTA Flash
dsDNA		 85.7 (79.3–90.7)  
kappa = 0.26  
(0.08–0.45)  		   78.9 (71.8–84.9)  
kappa = 0.39  
(0.22–0.55)  		 80.7 (73.8–86.5)  
kappa = 0.42  
(0.25–0.59)  		 83.9 (77.2–89.2)  
kappa = 0.37  
(0.17–0.56)  
N/A*   rho = 0.58
(0.46–0.67)
P < 0.0001		   rho = 0.46
(0.33–0.57)
P < 0.0001		 rho = 0.34
(0.19–0.47)
P < 0.0001
QUANTA Lite  
dsDNA SC		 77.0 (69.7–83.3)  
kappa = 0.17  
(0.04–0.30)  		 78.9 (71.8–84.9)
kappa = 0.39
(0.22–0.55)		   78.3 (71.1–84.4)  
kappa = 0.42  
(0.26–0.58)  		 80.1 (73.1–86.0)  
kappa = 0.38  
(0.22–0.54)  
N/A* rho = 0.58
(0.46–0.67)
P < 0.0001		     rho = 0.43
(0.30–0.55)  
P < 0.0001		 rho = 0.39  
(0.25–0.51)  
P < 0.0001
BioPlex 2200  
dsDNA		 78.9 (71.8–84.9)  
kappa = 0.18  
(0.04–0.32)  		 80.7 (73.8–86.5)
kappa = 0.42
(0.25–0.59)		 78.3 (71.1–84.4)
kappa = 0.42
(0.26–0.58)		   80.7 (73.8–86.5)
  kappa = 0.37  
(0.20–0.54)  
N/A* rho = 0.46
(0.33–0.57)
P < 0.0001		 rho = 0.43
(0.30–0.55)
P < 0.0001		   rho = 0.30  
(0.16–0.44)  
P < 0.0001
ImmuLisa  
dsDNA 		89.4% (83.6–93.7)  
kappa = 0.28  
(0.05–0.51)  		 83.9 (77.2–89.2)  kappa = 0.37  
(0.17–0.56)  		 80.1 (73.1–86.0)  
kappa = 0.38  
(0.22–0.54)  		 80.7 (73.8–86.5 )
kappa = 0.37  
(0.20–0.54)  		  
N/A* rho = 0.34  
(0.19–0.47)  
P < 0.0001		 rho = 0.39  
(0.25–0.51)  
P < 0.0001		 rho = 0.30  
(0.16–0.44)  
P < 0.0001		  

Note: total qualitative agreements are given in percent, followed by kappa statistics and Spearman's rho values (95% confidence intervals are provided in the parentheses). *NOVA Lite CLIFT was excluded from the analysis since it is a semiquantitative assay where grading values (0 to 4) are given by the operator.