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. 2015 Jan 27;2015:216798. doi: 10.1155/2015/216798

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Copyright © 2015 Gezina Tanya Mei Ling Oei et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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CINC-3 (a), IL-6 (b), IL-1β (c), and TNF-α (d) mRNA expression. Messenger RNA was analyzed in myocardial samples taken at the end of the experimental protocol. All animals underwent 15 min of stabilization and 25 min of ischemia (except for Sham) and 5, 15, or 30 min of reperfusion with or without helium. All data are shown as mean ± S.E.M. Amount of experiments in each group is shown below individual bars. To compare control (I/R) with helium intervention (I/R + He) at the various time points of reperfusion (5, 15, and 30 minutes), a two-way repeated measures ANOVA with Bonferroni correction for multiple testing was done. ^* P < 0.05 I/R in comparison to He.