Table 5.
HPV31 L1 sequence variations at the genome and protein level and the putative biological function affected.
| Genome Position | Variation | AA changed | Protein position (relative to HPV16 L1 gene) | Number of isolates | Biological function |
|---|---|---|---|---|---|
| 5926 | A/G | — | 1/4 | ||
| 5927 | T/C | — | 1/4 | ||
| 6025 | A/G | T267A | FG loop | 1/4 | MHC Class-I/HC Class-II |
| 6091 | C/T | — | 1/4 | ||
| 6335 | G/A | — | 1/4 | ||
| 6357 | A/G | — | 1/4 | ||
| 6374 | C/T | — | 1/4 | ||
| 6379 | C/A | T274N | FG loop | 1/4 | B-cell/MHC Class-I |
| 6593 | T/G | — | 1/4 |
(—) Synonymous variations with regard to the reference sequence J04353.1. T: threonine; N: asparagine; A: alanine.