Table 2.
Clinical and demographic characteristics of the cohort comparing sepsis patients without vs with shock
| Sepsis without shock (n = 42) | Sepsis with shock (n = 65) | p value | |
|---|---|---|---|
| Gender male (%) | 50 | 60 | 0.31 |
| Age (years,mean/sd) | 57.6(15.6) | 62.9(14.3) | 0.16 |
| Reason for admission (%): | 0.02 | ||
| Respiratory | 47.6 | 35.4 | |
| Abdominal | 14.3 | 41.5 | |
| Urinary | 14.3 | 1.5 | |
| Endocarditis | 2.4 | 6.2 | |
| Neurological | 4.8 | 1.5 | |
| Catheter | 4.8 | 3.1 | |
| Other | 11.9 | 10.8 | |
| CKD on admission (MDRD <60 mL/min/1,73 m2) (%) | 16.7 | 4.6 | 0.04 |
| APACHE II score on the first day of admission | 21(9) | 23(9) | 0.22 |
| AKI (transient or intrinsic) (%) | 25(59.5) | 54(83.1) | 0.007 |
| Fluid balance first 24 hours (liter, mean/sd) | 2.06(2.21) | 3.8(2.58) | <0.001 |
| Use of diuretics on the first day of admission (%) | 9.5 | 16.9 | 0.28 |
| RRT need during ICU stay (%) | 0 | 21.5 | 0.001 |
| Total dose of noradrenaline first 24 h in μg/kg/min (mean/sd) | N/A | 0.17(0.16) | N/A |
| Maximum dose of noradrenaline during first 24 h in μg/kg/min (mean/sd) | N/A | 0.44(0.41) | N/A |
| Need for ventilation during ICU stay (%) | 39.3 | 73.8 | <0.001 |
| LOS in the ICU (days) | 4(6) | 7(16) | 0.03 |
| ICU mortality (%) | 14.3 | 32.3 | 0.04 |
| Mortality at 90 days (%) | 19.0 | 41.5 | 0.02 |