Table 3.
Male DFF subjects | |||||||
---|---|---|---|---|---|---|---|
Male controls (n = 75) |
Mild trauma (n = 37) |
Moderate trauma (n = 36) |
All DFF subjects (n = 73) |
pa | pb | pc | |
Distal radius micro–finite element strength parameters | |||||||
Failure load (N) | 5832 ± 109 | 5353 ± 154 | 5995 ± 161 | 5661 ± 113 | 0.024 | 0.637 | 0.266 |
Fall load-to-strength ratio | 0.497 ± 0.010 | 0.543 ± 0.014 | 0.482 ± 0.014 | 0.514 ± 0.0101 | 0.013 | 0.639 | 0.212 |
Distal radius cortical parameters | |||||||
Ct.A (mm2) | 76.3 ± 1.6 | 70.0 ± 2.2 | 82.5 ± 2.3 | 76.0 ± 1.7 | 0.041 | 0.061 | 0.834 |
Ct.Th (mm) | 1.07 ± 0.02 | 1.01 ± 0.03 | 1.15 ± 0.03 | 1.07 ± 0.02 | 0.131 | 0.121 | 0.940 |
EC (mm) | 58.7 ± 0.7 | 58.3 ± 1.0 | 57.7 ± 1.0 | 58.0 ± 0.7 | 0.933 | 0.698 | 0.521 |
PC (mm) | 81.6 ± 0.7 | 80.0 ± 1.0 | 80.5 ± 1.1 | 80.3 ± 0.7 | 0.390 | 0.640 | 0.206 |
Ct.vBMD (mg/cm3) | 941 ± 4 | 936 ± 5 | 954 ± 5 | 944 ± 4 | 0.708 | 0.096 | 0.496 |
Ct.TMD (mg/cm3) | 961 ± 3 | 956 ± 5 | 974 ± 5 | 964 ± 3 | 0.505 | 0.080 | 0.593 |
Ct.Po (%) | 1.54 ± 0.09 | 1.41 ± 0.12 | 1.47 ± 0.13 | 1.44 ± 0.09 | 0.641 | 0.878 | 0.430 |
Distal radius trabecular parameters | |||||||
BV/TV | 0.175 ± 0.003 | 0.161 ± 0.004 | 0.172 ± 0.005 | 0.166 ± 0.003 | 0.014 | 0.763 | 0.037 |
Tb.N (1/mm) | 2.15 ± 0.02 | 2.04 ± 0.03 | 2.10 ± 0.03 | 2.07 ± 0.02 | 0.011 | 0.345 | 0.011 |
Tb.Th (mm) | 0.082 ± 0.001 | 0.079 ± 0.002 | 0.082 ± 0.002 | 0.080 ± 0.001 | 0.392 | 0.985 | 0.493 |
Tb.Sp (mm) | 0.39 ± 0.01 | 0.42 ± 0.01 | 0.40 ± 0.01 | 0.41 ± 0.01 | 0.003 | 0.378 | 0.006 |
DXA regional aBMD | |||||||
UD radius (g/cm2) | 0.572 ± 0.007 | 0.540 ± 0.010 | 0.587 ± 0.010 | 0.563 ± 0.008 | 0.024 | 0.444 | 0.368 |
Total radius (g/cm2) | 0.806 ± 0.008 | 0.764 ± 0.011 | 0.821 ± 0.011 | 0.792 ± 0.008 | 0.003 | 0.468 | 0.182 |
Spine (g/cm2) | 1.253 ± 0.016 | 1.197 ± 0.023 | 1.228 ± 0.023 | 1.212 ± 0.016 | 0.092 | 0.632 | 0.082 |
FN (g/cm2) | 1.134 ± 0.017 | 1.045 ± 0.025 | 1.133 ± 0.025 | 1.088 ± 0.018 | 0.007 | 0.999 | 0.065 |
Trochanter (g/cm2) | 0.969 ± 0.016 | 0.877 ± 0.022 | 0.934 ± 0.023 | 0.905 ± 0.016 | 0.002 | 0.363 | 0.005 |
Total hip (g/cm2) | 1.162 ± 0.017 | 1.071 ± 0.023 | 1.144 ± 0.024 | 1.107 ± 0.017 | 0.003 | 0.767 | 0.020 |
Total body (g/cm2) | 1.323 ± 0.010 | 1.265 ± 0.014 | 1.302 ± 0.014 | 1.283 ± 0.010 | 0.002 | 0.415 | 0.006 |
Values are presented mean ± SEM (adjusted for age, height, weight) and p values. Significant p values are in bold.
DXA = dual-energy X-ray absorptiometry; BMD = bone mineral density; DFF = distal forearm fracture; Ct.A = cortical area; Ct.Th = cortical thickness; EC = endocortical circumference; PC = periosteal circumference; Ct.vBMD = cortical volumetric bone mineral density; Ct.TMD = cortical tissue mineral density; Ct.Po = cortical porosity; BV/TV = bone volume/total volume; Tb.N = trabecular number; Tb.Th = trabecular thickness; Tb.Sp = trabecular separation; aBMD = areal BMD; UD = ultradistal; FN = femoral neck.
p = controls versus mild trauma subjects, using Dunnett’s adjustment for multiple comparisons.
p = controls versus moderate trauma subjects, using Dunnett’s adjustment for multiple comparisons.
p = controls versus all DFF subjects.