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. 2015 Mar;43(3):418–423. doi: 10.1124/dmd.114.061887

Fig. 3.

Fig. 3.

The mechanism of SULT1A1 inhibition. Inhibitor (EGCG or MEF) binds to each of the enzyme forms in the substrate portion of the catalytic cycle. Turnover (kcat) for the inhibited and noninhibited species are related by α.