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Summary of the voltage dependence of activation for hERG1 tetramers containing 0–4 L553A (LA) subunits
Data are expressed as mean ± S.E.M. (n = number of oocytes).
| Channel Type | V0.5act (mV) | Z | n |
|---|---|---|---|
| WT4 | −28.7 ± 0.7 | 3.76 ± 0.18 | 10 |
| LA1/WT3 | −31.0 ± 0.7 | 4.07 ± 0.11 | 5 |
| WT3/LA1 | −27.8 ± 0.6 | 3.61 ± 0.09 | 5 |
| LA2/WT2 | −29.7 ± 0.8 | 3.78 ± 0.12 | 5 |
| LA1/WT1/LA1/WT1 | −31.1 ± 0.1 | 3.87 ± 0.10 | 5 |
| LA1/WT1/LA2 | −32.6 ± 0.4 | 3.26 ± 0.16 | 4 |
| LA3/WT1 | −30.3 ± 1.0 | 3.54 ± 0.17 | 4 |
| LA4 | −30.6 ± 1.3 | 3.16 ± 0.31 | 4 |
