Table 2.
Odds Ratios (ORs) and 95% Confidence Intervals (CIs) for the Bivariate Association Between Adherence Barriers at 12 Weeks and Undetectable Plasma HIV RNA at 24 Weeks (N=1496)
| OR (95% CI) | p Value | |
|---|---|---|
| Adherence barriers | ||
| Away from home | 0.88 (0.68–1.13) | 0.32 |
| Busy with other things | 0.95 (0.72–1.26) | 0.73 |
| Simply forgot | 0.99 (0.76–1.30) | 0.95 |
| Too many pills to take | 0.43 (0.27–0.68) | <0.001 |
| Wanted to avoid side effects | 0.54 (0.38–0.77) | 0.001 |
| Not want others to notice you taking medications | 0.94 (0.62–1.43) | 0.77 |
| Change in daily routine | 0.82 (0.63–1.07) | 0.14 |
| Felt like the drug was toxic/harmful | 0.44 (0.28–0.70) | <0.001 |
| Fell asleep/slept through dose time | 0.84 (0.64–1.10) | 0.20 |
| Felt sick or ill | 0.49 (0.36–0.66) | <0.001 |
| Felt depressed/overwhelmed | 0.58 (0.40–0.84) | 0.004 |
| Problem taking pills at specified time | 0.71 (0.52–0.98) | 0.04 |
| Ran out of pills | 1.26 (0.67–2.37) | 0.48 |
| Felt good | 0.80 (0.54–1.19) | 0.27 |
| Summed adherence barriersa | - | 0.02b |
| 1 (1–4 ACTG barriers reported) | 0.85 (0.67–1.09) | 0.20 |
| 2 (≥5 ACTG barriers reported) | 0.64 (0.46–0.87) | 0.005 |
a
“No adherence barriers” as reference category; bOmnibus Wald test.