Table 2.
Number | |
---|---|
Donor | |
MSD | 8 |
MUD | 4 |
1 antigen mismatched related | 2 |
Cell type | |
G-CSF mobilized peripheral blood stem cells | 10 |
Bone marrow | 4 |
Conditioning | |
Reduced-intensity (Melphalan-based) | |
Melphalan 140 mg/m2 + fludarabine 120 mg/m2 + Gemtuzumab (2, 4, 6, 9 or 16 mg/m2) | 8 |
Melphalan 100 mg/m2 + fludarabine 120 mg/m2 | 1 |
Myeloablative (Busulfan-based) | |
i.v. Busulfan 520 mg/m2 + fludarabine 160 mg/m2 | 3 |
i.v. Busulfan 520 mg/m2 + clofarabine 120 mg/m2 + fludarabine 40 mg/m2 | 1 |
p.o. Busulfan 1 mg/kg × 10 doses + cyclophosphamide 120 mg/kg + thiotepa 750 mg/m2 | 1 |
GVHD prophylaxis | |
Tacrolimus + methotrexate | 13 |
Cyclosporine + methotrexate | 1 |
MSD indicates matched sibling donor; MUD, matched unrelated donor; i.v., intravenous; p.o., oral; GVHD, graft-versus-host disease; G-CSF, granulocyte colony-stimulating factor.