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. Author manuscript; available in PMC: 2015 Mar 9.
Published in final edited form as: Biol Blood Marrow Transplant. 2010 Jan 29;16(4):555–559. doi: 10.1016/j.bbmt.2009.12.004

Table 3.

Outcomes of 14 Patients with Myelofibrosis and Leukemic Transformation Treated with Allogeneic Stem Cell Transplantation

Primary engraftment (%)* 100%
Engraftment (median, range)
    Day to ANC 500 (N = 14) 13 (8-21)
    Days to platelet count 20,000 (N = 11) 21.5 (13-40)
Chimerism at day 30 by PCR* (N = 14)
    100% 11
    85%-99% 2
    Not tested 1
Median follow-up survivors, months (range) 31 (10-127)
aGVHD, n
    Grade II-IV 5
    Grade III-IV 2
cGVHD, n
    All grades 5
    Extensive 2
Complete remission after transplant, n 14
Disease progression
    n (% CI) 4 (38%) (16-89)
NRM, Overall
    n (% CI) 4 (29%) (12-65)
PFS, Overall
    n (% CI) 6 (33%) (7-63)
OS, Overall
    n (% CI) 7 (49%) (22-72)

ANC indicates absolute neutrophil count; PCR, polymerase chain reaction; aGVHD, acute graft-versus-host-disease; cGVHD, chronic graft-versus-host disease; NRM, nonrelapse mortality; PFS, progression-free survival; OS, overall survival; CI, cumulative incidence.

*

Donor myeloid and T cells.

95% Confidence interval.