An 83-year-old man with left hemiparesis and aphasia was treated with intravenous tissue plasminogen activator within 2.5 hours after onset (patient 5).
(A) The admission computed tomography (CT) showed hyperdense middle cerebral artery sign (arrow) in the right side. Initial diffusion weighted imaging (B) and apparent diffusion coefficient (C; 3 hours after admission CT) showed restricted diffusion in the right middle cerebral artery territory.
(D) Post-Gd T1-weighted image showed hyperintense middle cerebral artery sign in the right middle cerebral artery stem (arrow).
(E) Digital subtraction angiography showed proximal segment occlusion of right middle cerebral artery (arrow).
(F) Follow-up of gradient echo interleaved Echo Planar Imaging on day 3 showed hemorrhage in the right middle cerebral artery territory.