TABLE 1.
Characteristics of men who have sex with men with no history of injection drug use who were included and excluded from the analysis of hepatitis C virus (HCV) seroincidence, Ontario HIV Treatment Network Cohort Study, 2000 to 2010
| Characteristic | Included (n=1534) | Excluded (n=1227) | P† |
|---|---|---|---|
| Age at baseline*, years | |||
| <30 | 150 (9.8) | 92 (7.5) | 0.14 |
| 30–39 | 541 (35.3) | 425 (34.6) | |
| 40–49 | 584 (38.1) | 482 (39.3) | |
| ≥50 | 259 (16.9) | 228 (18.6) | |
| Mean ± SD | 41±9.4 | 42±9.4 | 0.009 |
| Region (Ontario) | |||
| Toronto | 1142 (74.4) | 755 (61.5) | <0.0001 |
| Ottawa | 80 (5.2) | 205 (16.7) | |
| Other | 312 (20.3) | 267 (21.8) | |
| Race‡ | |||
| White | 1144 (74.6) | 971 (79.1) | 0.009 |
| Black | 72 (4.7) | 37 (3.0) | |
| Aboriginal | 121 (7.9) | 70 (5.7) | |
| Other race | 194 (12.7) | 149 (12.1) | |
| Year of HIV diagnosis, median (IQR) | 1996 (1990–2003) | 1993 (1989–1999) | <0.0001 |
| Initiated antiretroviral treatment at baseline* | 963 (62.8) | 800 (65.2) | 0.19 |
| Initiated antiretroviral treatment as of last follow-up | 1419 (92.5) | 1156 (94.2) | 0.07 |
| CD4 cell count/mm3 at baseline*, mean ± SD | 421±260 | 403±254 | 0.13 |
| Log10 viral load at base-line*, median (IQR) | 2.88 (1.69–4.53) | 2.42 (1.69–4.14) | 0.0005 |
| Ever HCV-positive at last follow-up | |||
| No | 1483 (96.7) | 1132 (92.3) | <0.0001 |
| Yes | 51 (3.3) | 95 (7.7) |
Data presented as n (%) unless otherwise indicated.
*
Baseline was defined as the later of the first HCV-negative test, the first HIV-positive date, or January 1, 2000;
†
P values were calculated using χ2 tests for categorical variables, Wilcoxon signed-rank for medians or Student’s t tests for means, as appropriate;
‡
Excludes 15 men with unknown race. IQR Interquartile range