TABLE 1.
Oseltamivir and zanamivir treatment of influenza
| Updated from: The use of antiviral drugs for influenza: A foundation document for practitioners (6) | |||
| Medication | Treatment (5 days) | Chemoprophylaxis (10 days) | |
|
| |||
| Oseltamivir1 | |||
|
| |||
| Adults | |||
|
| |||
| 75 mg twice daily | 75 mg once daily Children ≥12 months |
||
|
| |||
| Body weight (kg) | Body weight (lbs) | ||
| ≤15 kg | ≤33 lbs | 30 mg twice daily | 0 mg once daily |
| >15 kg to 23 kg | >33 lbs to 51 lbs | 45 mg twice daily | 45 mg once daily |
| >23 kg to 40 kg | >51 lbs to 88 lbs | 60 mg twice daily | 60 mg once daily |
| >40 kg | >88 lbs | 75 mg twice daily | 75 mg once daily |
| Children 3 months to <12 months2* | |||
|
| |||
| 3 mg/kg/dose twice daily Children <3 months3* |
3 mg/kg/dose once per day | ||
| 3 mg/kg/dose twice daily | Not recommended unless situation judged critical due to limited data on use in this age group | ||
*
Please note that antivirals are not authorized for the routine treatment of seasonal influenza illness in infants <1 year of age. Such use may be considered on a case-by-case basis.