Table 3.
Effectiveness of the 2011 and 2012 Southern Hemisphere influenza vaccines in various scenarios
| 2011 Southern Hemisphere vaccine | 2012 Southern Hemisphere vaccine | ||||
|---|---|---|---|---|---|
| Scenario | Vaccination status | Vaccine effectiveness | 95% confidence interval | Vaccine effectiveness | 95% confidence interval |
| Adjust for age at ARI (continuous variable) and the presence of underlying medical condition | Full | 57 | –46, 87 | 64 | 12, 85 |
| Exclude ARI episodes occurring during the last 6 months of season | Full | 55 | –72, 88 | 64 | 13, 85 |
| Exclude all ARI episodes in persons treated with oseltamivir before swab collection | Full | 75 | –53, 96 | 57 | –31, 86 |
| Exclude ARI episodes that tested positive for A(H3N2) in 2012–2013 season | Full | n/a | n/a | 63 | 2, 86 |
| Re-classify children with 1st 2 doses administered <28 days apart as fully vaccinated | Full | 57 | –67, 89 | 64 | 13, 85 |
| Exclude episodes with specimens collected =7 days of illness onset | Full | 78 | –31, 96 | 61 | 50, 84 |
| Shorten time between last vaccination and onset of illness from 14 to 7 days | Full | 58 | –64, 89 | 65 | 13, 86 |
| Include only children aged <36 months | Full | 46 | –103, 86 | 79 | 29, 94 |
| Include only children with ≤3 months between vaccination and ARI onset | Full | * | * | 3 | –154, 63 |
| Include only children with =3–6 months between vaccination and ARI onset | Full | * | * | 61 | –12, 87 |
| Include only children with =6–9 months between vaccination and ARI onset | Full | * | * | 84 | 6, 97 |
ARI, acute respiratory illness; n/a, not applicable.
Could not be calculated due to small sample size.