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Figure The placement of α2 varies among LOXs. The “arched” helix and helix α2 in the plant (green, 1YGE) animal (flesh, 4QWT) and bacterial enzymes (light blue, 4G32) are superimposed. The “broken” α2 (brown, 3O8Y) of 5-LOX is included as well for reference. Note that while the arched helices from the diverse structure superpose, α2 varies in its placement.
