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. 2015 Mar 1;13:77. doi: 10.1186/s12967-015-0428-x

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© Ascierto et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Analysis of pre-treatment NK cells trascriptome according to the level of HCV viremia. A) Supervised cluster based on 165 genes derived from Student’s t Test Chronic Viraemic HCV patients (CV-HCV) vs. HD (Cut off p value <0.005; FC > 1.5). B) Venn diagram between the 476 genes able to differentiate NR vs. SVR patients and the 165 genes associated with viremia. Among the genes able to segregate the SVR from the NR, only 22 genes (5%) were affected by viremia.