Table 1.
Anti-HAdv5 antibody in sera from tumor bearing hamsters treated with adenoviral vectors
Serum (HPT11) | Serological test | Serum (HPT 12) | Serological test |
---|---|---|---|
Subcutaneous tumors | |||
Vehicle | - | Vehicle | 40 |
Ip11w | 720 | Ip11w | 180 |
Ip11w/Δ55K | 960 | Ip11w/Δ55K | 240 |
Ad5 wt | 1280 | ||
Pouch tumors | |||
Vehicle | - | Vehicle | - |
Ip11w | 480 | Ip11w | 1440 |
Ip11w/Δ55K | 640 | Ip11w/Δ55K | 640 |
Neutralizing antibody titers are expressed as the highest reciprocal serum dilutions. Average antibody titers from two animals from each group are presented. Hyper immunized serum raised against HAdV5 wt virus from hamster was used for positive control.