. Author manuscript; available in PMC: 2015 Mar 9.

Published in final edited form as: Environ Mol Mutagen. 2013 Aug 1;54(7):566–573. doi: 10.1002/em.21801

TABLE 2.

Top 10 Pathways Altered by Benzene Exposure

KEGG pathway name	P
Fc epsilon RI signaling pathway^a	0.000
MAPK signaling pathway^a	0.000
Adipocytokine signaling pathway^a	0.001
Leishmaniasis	0.001
Cysteine and methionine metabolism	0.002
Type II diabetes mellitus	0.002
Graft-versus-host disease	0.003
Pancreatic cancer^a	0.003
Insulin signaling pathway^a	0.004
Proteasome	0.005

This pathway was detected as significant in either one of the two highest dose ranges of benzene exposure in the earlier microarray analyses [McHale et al., 2011].