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Amino acid sequence comparison between mENG and hENG in the region encoded by exons 4–8. The conserved regions between mENG and hENG are indicated by shades. Amino acid residues whose mutations are associated with HHT1 by relevant mutations, i.e., missense mutations or single amino acid deletions, are indicated by bold letters. The data of these mutations are from the HHT Mutation Database (http://www.hhtmutation.org/).
