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. Author manuscript; available in PMC: 2015 Mar 9.
Published in final edited form as: Am J Med Genet A. 2013 Dec 19;0(2):432–440. doi: 10.1002/ajmg.a.36324

TABLE IV.

Distribution of Demographic Characteristics by Spina Bifida Classification, Pre- and Post-Fortification

Pre-fortificationa
Post-fortificationb
Isolated SB (n = 733)
Non-isolated SB (n = 147)
Isolated SB (n = 185)
Non-isolated SB (n = 71)
n % n % n % n %
Infant sex
 Male 315 43.0 70 47.6 87 47.0 36 50.7
 Female 390 53.2 73 49.7 93 50.3 34 47.9
 Unknown 28 3.8 4 2.7 5 2.7 1 1.4
Maternal race/ethnicity
 White, non-Hispanic 681 92.9 130 88.4 109 58.9 46 64.8
 Black, non-Hispanic 24 3.3 10 6.8 24 13.0 3 4.2
 Other racesc 28 3.8 7 4.8 52 28.1 22 31.0
 Hispanic (1983+) 15 2.0 5 3.4 38 20.5 18 25.4
Maternal age at conception
 <20 years 57 7.8 18 12.2 16 8.6 4 5.6
 20–29 years 430 58.7 82 55.8 81 43.8 44 62.0
 ≥30 years 246 33.6 47 32.0 88 47.6 23 32.4
Maternal education
 <12 years 109 14.9 28 19.0 30 16.2 9 12.7
 12 years 289 39.4 62 42.2 37 20.0 25 35.2
 >12 years 334 45.6 57 38.8 117 63.2 37 52.1
 Missing data 1 0.1 0 0.0 1 0.5 0 0.0
Folic acid intake
 ≥400 μg 129 17.6 22 15.0 94 50.8 33 46.5
 <400 μg 567 77.4 117 79.6 82 44.3 36 50.7
 Missing data 37 5.0 8 5.4 9 4.9 2 2.8
a

LMP dates prior to January 1, 1996.

b

LMP dates on or after January 1, 1998.

c

Other races includes Hispanic race/ethnicity.