Table 7.

Body and organ weights in PND 23 male offspring

	Control 0 ppm	HMB dose group (ppm)
		1,000	3,000	10,000	25,000	50,000
Body weight (BW)(g)	37.66 ± 3.28	41.79 ± 2.05	35.39 ± 1.91	35.67± 2.46	29.58 ± 1.13*	24.8 ± 3.68*
Paired testes weights (g)	0.24 ± 0.02	0.28 ± 0.02	0.23 ± 0.01	0.23 ± 0.02	0.19 ± 0.01	0.16 ± 0.03*
Relative paired testes weights/BW (g/10g BW)	0.063 ± 0.001	0.067 ± 0.003	0.069 ± 0.006	0.065 ± 0.002	0.064 ± 0.001	0.064 ± 0.003
Paired epididymides weights (g)	0.036 ± 0.002	0.039 ± 0.002	0.038 ± 0.003	0.040 ± 0.003	0.028 ± 0.001	0.026 ± 0.001
Relative paired epididymides weights/BW (g/10g BW)	0.010 ± 0.001	0.009 ± 0.001	0.012 ± 0.002	0.011 ± 0.001	0.009 ± 0.0003	0.011 ± 0.0009
Liver weight (g)	1.32 ± 0.15	1.57 ± 0.15	1.43 ± 0.17	1.52 ± 0.16	1.18 ± 0.06	0.96 ± 0.17
Relative liver weight/BW (g/10g BW)	0.35 ± 0.01	0.37 ± 0.02	0.42 ± 0.03	0.42 ± 0.02	0.40 ± 0.01	0.38 ± 0.01
Paired kidney weights (g)	0.39 ± 0.04	0.42 ± 0.02	0.35 ± 0.01	0.37 ± 0.03	0.30 ± 0.01	0.25 ± 0.04*
Relative paired kidney weights/BW (g/10g BW)	0.102 ± 0.001	0.101 ± 0.001	0.107 ± 0.010	0.103 ± 0.002	0.102 ± 0.001	0.103 ± 0.001
N	6	5	7	8	7	4

Values are mean ± SEM of all male pups in the litter.

^*p ≤ 0.05 compared to the control (0 ppm) group.

N indicates number of animals per dose group.