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. Author manuscript; available in PMC: 2015 Mar 9.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2011 Jul 15;3(6):702–716. doi: 10.1002/wsbm.154

Fig. 6.

Fig. 6

High resolution AFM images of pores formed by amyloid beta 1–42 (A)48 and amyloid beta 17–42 (B)95 oligomers in lipid bilayers. Open (C) and close (D) conformations of connexin-43 hemichannels in the absence and presence of 1.8 mM Ca++ respectively.16 Real time aggregation of VEGF receptors on the surface of a endothelial cell before (E) and after (F) the addition of VEGF-antibody.29 Real time proteolysis of collagen molecules before (G) and after (H) the addition of collagenase.98 Shear stress induced reorganization of cytoskeleton in living endothelial cells imaged by AFM.105 Under static conditions (I), the cells topography is smooth and under unidirectional shear stress the topography is reorganized (J) to minimize the shear stress gradient to reduce resistance to flow.