. Author manuscript; available in PMC: 2015 Dec 2.

Published in final edited form as: Structure. 2014 Nov 13;22(12):1744–1753. doi: 10.1016/j.str.2014.10.001

Table 1.

Contractile activity on rat stomach fundus exerted by TLQP-21 mutants (mutation highlighted in bold).

Peptide	Activity % of TLQP-21 (average ± SEM)
TLQPPASSRRRHFHHALPPAR	100
TLQPPASSRRR	inactive
HFHHALPPAR	2.6±4^***
TLQPPASSRRRAFHHALPPAR	95±4
TLQPPASSRRRHAHHALPPAR	88±9
TLQPPASSRRRHFAHALPPAR	91±5
TLQPPASSRRRHFHAALPPAR	84±10
TLQPPASSRRRHFHHALAPAR (P18A)	65±7 ^*
TLQPPASSRRRHFHHALPAAR (P19A)	19±4 ^***
TLQPPASSRRRHFHHALPPAA (R21A)	inactive
TLQPPASSRRRHFHHALPPAR-NH2	inactive
TLQPPSALRRRHYHHALPPSR (human)	20±9^**

p>0.5

^**

<0.01

^***

<0.001.