Table 1.
Parameters of wheel running activity in female WT and VIP−/− mice.
WT | VIP−/− | |
---|---|---|
LD | ||
LD activity, rev/hr | 331.96 ± 27.95 | 280.08 ± 25.18 |
LD phase angle, min | −7.98 ± 4.02 | −8.70 ± 8.55 |
LD precision, min | −17.79 ± 4.25 | −23.25 ± 10.14 |
LD fragmentation, bouts/day | 4.95 ± 0.33 | 6.83 ± 0.63* |
DD | ||
LD to DD phase angle, hr | −0.35 ± 0.11 | −3.85 ± 1.40** |
Tau, hr (DD) | 23.69 ± 0.06 | 23.15 ± 0.15** |
DD power, %V | 44.75 ± 4.67 | 29.68 ± 3.00** |
DD activity, rev/hr | 311.64 ± 33.88 | 364.28 ± 47.62 |
DD precision, min | −38.82 ± 12.10 | −302.98 ± 71.08*** |
DD fragmentation, bouts/day | 6.19 ± 0.49 | 5.72 ± 0.49 |
Phase shift to light at CT 16 | 162.8 ± 18.4 | −7.14 ± 12.63*** |
Values are reported as mean ± S.E.M. n = 10 for WT and n = 10 for VIP−/− females. LD, light dark cycle; DD, constant darkness; rev, wheel revolutions, %V, normalized Qp.
Significant differences between WT and VIP−/− mice are indicated with for P < 0.05
for P < 0.01
for P < 0.001.