. Author manuscript; available in PMC: 2015 Mar 9.

Published in final edited form as: J Biol Rhythms. 2014 Sep 24;29(5):355–369. doi: 10.1177/0748730414549767

Table 3.

PER2::LUC bioluminescence parameters of WT and VIP−/− ex vivo explants.

	WT	VIP−/−
SCN
Period (hr)	25.84 ± 0.54	25.62 ± 0.60
Phase (first calculated peak)	14.38 ± 0.56	13.24 ± 1.47
Amplitude	154.10 ± 13.82	87.40 ± 19.57^*
Damping Rate	−0.61 ± 0.05	−0.42 ± 0.04^**
R²	0.972 ± 0.015	0.968 ± 0.006

Pituitary
Period (hr)	23.54 ± 0.23	23.98 ± 0.68
Phase (first calculated peak)	16.96 ± 0.27	14.86 ± 0.66^*
Amplitude	414.01 ± 60.65	138.67 ± 19.95^**
Damping Rate	−0.45 ± 0.03	−0.59 ± 0.05^*
R²	0.992 ± 0.002	0.967 ± 0.009^*

Liver
Period (hr)	25.73 ± 1.24	25.32 ± 0.62
Phase (first calculated peak)	18.12 ± 0.33	13.47 ± 0.63^***
Amplitude	27.02 ± 10.40	102.54 ± 20.25^**
Damping Rate	−0.40 ± 0.04	−0.38 ± 0.09
R²	0.824 ± 0.037	0.797 ± 0.087

Heart
Period (hr)	24.90 ± 0.51	24.45 ± 0.41
Phase (first calculated peak)	19.81 ± 0.91	14.91 ± 0.52^***
Amplitude	50.62 ± 11.68	38.52 ± 8.53
Damping Rate	−0.53 ± 0.03	−0.42 ± 0.04
R²	0.985 ± 0.005	0.943 ± 0.014

Adrenal Glands
Period (hr)	24.40 ± 0.53	23.70 ± 0.90
Phase (first calculated peak)	13.47 ± 1.43	11.94 ± 1.55
Amplitude	24.31 ± 3.63	26.84 ± 4.41
Damping Rate	−0.57 ± 0.05	−0.58 ± 0.05
R²	0.678 ± 0.069	0.692 ± 0.028

Ovary
Period (hr)	22.93 ± 0.53	24.25 ± 0.55
Phase (first calculated peak)	12.09 ± 1.52	10.85 ± 0.90
Amplitude	170.71 ± 49.90	167.29 ± 65.56
Damping Rate	−0.57 ± 0.08	−0.53 ± 0.04
R²	0.923 ± 0.043	0.899 ± 0.039

Uterus
Period (hr)	24.00 ± 0.40	24.05 ± 0.49
Phase (first calculated peak)	16.06 ± 1.32	11.39 ± 1.52^*
Amplitude	218.35 ± 70.77	230.47 ± 53.74
Damping Rate	−0.47 ± 0.15	−0.45 ± 0.06
R²	0.867 ± 0.053	0.815 ± 0.072

Values are reported as mean ± S.E.M. n = 7 for WT and n = 10 for VIP−/−. Significant differences determined by Student’s t-tests between WT and VIP−/− mice are indicated with

for P < 0.05

^**

for P < 0.01

^***

for P < 0.001.