Table 1. Characteristics of the patients with RCC and correlations between subcellular pontin expression and clinicopathological variables (n = 95).
Variables | No. of pts | Cytoplasmic pontin expression | P-value | Nuclear pontin expression | P-value | ||
---|---|---|---|---|---|---|---|
High | Low | High | Low | ||||
Patients' age | |||||||
≥ 55 Years | 38 | 9 | 29 | 0.511 | 9 | 29 | 0.229 |
< 55 Years | 57 | 17 | 40 | 8 | 49 | ||
Gender | |||||||
Male | 75 | 19 | 56 | 0.389 | 15 | 60 | 0.512 |
Female | 20 | 7 | 13 | 2 | 18 | ||
T stage | |||||||
T1 | 41 | 8 | 33 | 0.057 | 9 | 23 | 0.351 |
T2 | 22 | 4 | 18 | 5 | 17 | ||
T3 | 21 | 8 | 13 | 1 | 20 | ||
T4 | 11 | 6 | 5 | 2 | 9 | ||
N stage | |||||||
N0 | 84 | 22 | 62 | 0.486 | 15 | 69 | 0.979 |
N1,2 | 11 | 4 | 7 | 2 | 9 | ||
M stage | |||||||
M0 | 83 | 19 | 64 | 0.010 | 13 | 70 | 0.218 |
M1 | 12 | 7 | 5 | 4 | 8 | ||
TNM stage | |||||||
I,II | 56 | 10 | 46 | 0.003 | 11 | 45 | 0.594 |
III,IV | 39 | 16 | 23 | 6 | 33 | ||
Histological grade | |||||||
G1,2 | 47 | 8 | 39 | 0.025 | 4 | 43 | 0.030 |
G3,4 | 48 | 18 | 30 | 13 | 35 | ||
Histological type | |||||||
Clear cell | 68 | 17 | 51 | 0.168 | 12 | 56 | 0.849 |
Papillary | 13 | 6 | 7 | 3 | 10 | ||
Chromophobe | 10 | 1 | 9 | 1 | 9 | ||
Unclassified | 4 | 2 | 2 | 1 | 3 |
Abbreviations: RCC = renal cell carcinoma.