Table 2.
Summary of the dose differences calculated by the AAA and AXB algorithm with 2.5 and 1 mm CGS for the 10XFFF beam
| Structures | Metrics | Unit | AAA 2.5mm | AXB 2.5mm | AAA 1mm | AXB 1mm |
|---|---|---|---|---|---|---|
| PTV_lung | Dmin | Gy | 44.2 ± 0.7 | 39.9 ± 2.1a | 44.5 ± 0.7 | 40.4 ± 2.9b |
| Dmax | Gy | 57.4 ± 1.2 | 57.8 ± 2.0 | 58.5 ± 0.9 | 58.3 ± 1.8 | |
| Dmean | Gy | 51.9 ± 0.6 | 50.5 ± 1.6a | 52.7 ± 0.6 | 50.9 ± 1.3b | |
| PTV_soft | Dmin | Gy | 47.6 ± 2.9 | 47.4 ± 3.0 | 47.4 ± 2.8 | 46.9 ± 2.6 |
| Dmax | Gy | 57.1 ± 2.0 | 57.7 ± 2.4 | 57.8 ± 2.0 | 58.3 ± 2.2b | |
| Dmean | Gy | 53.5 ± 1.7 | 53.3 ± 1.8 | 53.5 ± 1.8 | 53.4 ± 1.8 | |
| Aorta | Dmax | Gy | 13.7 ± 10.1 | 13.7 ± 10.2 | 13.8 ± 10.1 | 13.8 ± 10.0 |
| Dmean | Gy | 2.8 ± 2.5 | 2.7 ± 2.4a | 2.8 ± 2.5 | 2.7 ± 2.4b | |
| Bronchial tree | Dmax | Gy | 14.8 ± 10.0 | 14.9 ± 10.1 | 15.0 ± 10.0 | 15.0 ± 10.0 |
| Dmean | Gy | 3.9 ± 2.8 | 3.9 ± 2.8 | 3.9 ± 2.8 | 3.9 ± 2.8 | |
| Chest wall | V45 | % | 1.3 ± 2.0 | 1.3 ± 2.0 | 1.4 ± 2.1 | 1.3 ± 2.0 |
| V30 | % | 8.1 ± 9.5 | 7.9 ± 9.1 | 8.2 ± 9.5 | 8.0 ± 9.2b | |
| V20 | % | 36.3 ± 30.6 | 35.1 ± 30.0a | 37.1 ± 30.8 | 35.9 ± 30.2 | |
| Dmean | Gy | 5.5 ± 2.4 | 5.4 ± 2.4a | 5.5 ± 2.4 | 5.4 ± 2.4b | |
| Spinal cord | Dmax | Gy | 9.4 ± 3.8 | 9.1 ± 3.7a | 9.5 ± 3.8 | 9.3 ± 3.7b |
| Dmean | Gy | 1.6 ± 0.6 | 1.6 ± 0.5a | 1.6 ± 0.6 | 1.6 ± 0.5b | |
| Esophagus | Dmax | Gy | 9.9 ± 3.6 | 9.8 ± 3.7 | 10.0 ± 3.5 | 10.0 ± 3.7 |
| Dmean | Gy | 2.1 ± 0.8 | 2.1 ± 0.8a | 2.1 ± 0.8 | 2.1 ± 0.8b | |
| Heart | Dmax | Gy | 18.0 ± 10.1 | 18.2 ± 11.0 | 18.1 ± 10.8 | 18.3 ± 10.9 |
| Dmean | Gy | 1.5 ± 1.3 | 1.5 ± 1.3a | 1.5 ± 1.3 | 1.5 ± 1.3b | |
| Ipsilateral lung | V5 | % | 25.4 ± 8.1 | 26.5 ± 8.3a | 25.2 ± 8.1 | 26.4 ± 8.3b |
| V10 | % | 17.7 ± 7.8 | 18.0 ± 8.0a | 17.7 ± 7.8 | 18.0 ± 8.0b | |
| V20 | % | 7.9 ± 4.4 | 8.0 ± 4.5 | 8.0 ± 4.5 | 8.0 ± 4.5 | |
| Dmean | Gy | 5.2 ± 2.0 | 5.2 ± 2.0a | 5.2 ± 2.0 | 5.2 ± 2.1 | |
| Contralateral lung | V5 | % | 1.6 ± 1.4 | 1.5 ± 1.4 | 1.7 ± 1.5 | 1.6 ± 1.5b |
| Dmean | Gy | 1.0 ± 0.4 | 1.0 ± 0.4 | 1.0 ± 0.4 | 1.0 ± 0.4 |
Abbreviations: PTV_lung = PTV with a density in the lung range; PTV_soft = PTV with a density in the soft-tissue range; Dmin = minimum dose; Dmax = maximum dose; Dmean = mean dose; Vx was the volume of the organ receiving a dose of x or more; aWilcoxon signed-rank tests with p value <0.05 between AXB and AAA plan with 2.5 mm CGS; bWilcoxon signed-rank tests with p value <0.05 between AXB and AAA plan with 1 mm CGS.