Table 3.
Islet morphometry
| AD-CON (n = 5) | AD-LSP (n = 5) | AD-MSP (n = 5) | AD-SSP (n = 5) | Non-AD-CON (n = 5) | |
|---|---|---|---|---|---|
| β-cell area (%) | 5.3 ± 1.1b | 6.4 ± 0.9b | 5.9 ± 0.8ab | 5.7 ± 1.0ab | 7.9 ± 1.0a |
| Individual β-cell size (μm2) | 261 ± 30a | 228 ± 29b | 235 ± 28b | 241 ± 27ab | 234 ± 27b |
| Absolute β-cell mass (mg) | 21.0 ± 3.1b | 24.7 ± 2.9a | 24.0 ± 2.9a | 23.5 ± 2.8ab | 24.9 ± 2.9a |
| BrdU+ cells (% BrdU+ cells of islets) | 0.94 ± 0.13 | 1.03 ± 0.12 | 1.05 ± 0.11 | 1.06 ± 0.12 | 1.01 ± 0.14 |
| Apoptosis (% apoptotic bodies of islets) | 1.19 ± 0.16a | 0.97 ± 0.12b | 1.02 ± 0.12b | 1.02 ± 0.13b | 0.95 ± 0.13b |
Values are Means ± SD. The β-amyloid (25–35) infused diabetic rats fed high fat diets with 1% dextrin (AD-CON), 1% less pungent red pepper (AD-LSP), moderately pungent red pepper (AD-MSP) or severely pungent red pepper (AD-SSP) for 28 days. The β-amyloid (35–25) infused rats fed high fat diets with 1% dextrin (Non-AD-CON).
abDifferent superscript alphabets on the same row indicate significant differences at P < 0.05.