Table 1.
Sequence Conservation of the PADEGYP and PGRRGYP Motifs in the A/V-ATPase A and B Subunits, Respectively, and DEXE/DRED/EFF/YRLK Motif in Subunit D
| A/V-ATPase Subunit A PADEGYP Motif |
A/V-ATPase Subunit B PGRRGYP Motif |
A/V-ATPase Subunit D DEXE/DRED/EFF/YRXK |
|---|---|---|
| P(100) | P(99.7) A(0.3) | D(96.5) E(3) G(0.5) |
| A(59.7) G(40.3) | G(94.6) S(5.4) | E(100) |
| D(65) E(35) | R(100) | X |
| E(44) S(36.7) Q(14.3) A(4) G(1) N(0.3) Y(0.3) | R(84.3) K(12.4) Q(2.3) G(1) | E(61) D(38) S(0.5) A(0.5) |
| G(100) | G(99) S(1) | R(100) |
| Y(84) F(16) | Y(85.6) F(14.4) | E(99.5) Q(0.5) |
| P(100) | P(100) | E(81) D(18) N(0.5) R(0.5) |
| F(99) I(0.5) C(0.5) | ||
| F(48.8) Y(42) T(4.2) V(4) | ||
| R(100) | ||
| L(95) M(2.5) I(2.5) | ||
| K(99.5) M(0.5) |
The conservation at each position is based on alignment of 300 sequences and is shown in parentheses as a percentage.