Table III.
Changes in the food consumption (g) in the high-fat diet-induced hyperlipemic hamster model.
| Time points | Sham | Control | SIMVA | Polycan groups (mg/kg) | ||
|---|---|---|---|---|---|---|
|
| ||||||
| 31.25 | 62.5 | 125 | ||||
| Day 1 | 6.74 | 5.12 | 4.98 | 5.10 | 5.36 | 5.58 |
| Day 7 | 6.10 | 4.04 | 5.94 | 5.34 | 5.76 | 5.08 |
| Day 14 | 5.94 | 4.64 | 5.28 | 5.34 | 4.54 | 5.70 |
| Day 21 | 6.02 | 5.66 | 5.34 | 6.12 | 4.30 | 4.30 |
| Day 28 | 8.14 | 4.26 | 4.54 | 5.72 | 4.44 | 4.92 |
| Day 35 | 8.44 | 6.30 | 4.25 | 5.20 | 5.20 | 5.78 |
| Day 42 | 8.93 | 5.66 | 5.71 | 4.80 | 5.90 | 6.43 |
| Day 49 | 7.22 | 5.80 | 6.22 | 4.22 | 5.80 | 5.75 |
| Day 55 | 7.12 | 6.23 | 5.89 | 4.33 | 5.72 | 5.16 |
| Meana | 7.18±1.11 | 5.30±0.83b | 5.35±0.66b | 5.13±0.61b | 5.22±0.64b | 5.41±0.62b |
a
Results are expressed as the mean ± standard deviation (n=5).
b
P<0.01, vs. sham (MW test).
SIMVA, simvastatin; MW, Mann-Whitney-Wilcoxon.