Table VI.

Changes to the histomorphometry of the liver and aorta in the high-fat diet-induced hyperlipemic hamster model.

Group	Fatty change regions (%/200 μm2 liver parenchyma)	Atherosclerotic plaques (%/1 mm aorta surface)
		Abdominal aorta	Thoracic aorta
Sham	0.86±0.39	0.64±0.56	0.43±0.17
Control	93.94±2.88a	8.12±1.89a	8.32±2.33a
SIMVA	94.61±2.73a	1.55±0.48b,c	1.02±0.19a,c
Polycan 31.25	84.76±4.93a,c	4.54±1.20a,c	2.83±0.87a,c
Polycan 62.5	77.60±8.62a,c	2.70±1.13a,c	2.11±0.69a,c
Polycan 125	76.61±8.74a,c	2.40±1.36b,c	1.60±0.93a,c

Results are expressed as the mean ± standard deviation (n=5).

^aP<0.01 and

^bP<0.05, vs. sham (MW test);

^cP<0.01, vs. vehicle control (MW test).

SIMVA, simvastatin; MW, Mann-Whitney-Wilcoxon.