Figure 4.

Co-localization of BrdU and osteocalcin expression in the midpalatal suture. Positive signals due to labeling with BrdU in the (A) EaT and (B) EtR groups revealed that transplanted BMMCs survived and appeared in the fibrous-like tissues. Co-expression was observed in certain (C) proliferating cells adjacent to the palatal bone of the EaT group and (D) osteocytes in the newly forming bone of the EtR group. BrdU, bromodeoxyuridine; EaT, expansion and transplantation; EtR, expansion, transplantation and relapse; BMMC, bone marrow mononuclear cell.