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. 2015 Feb 13;9(4):1537–1541. doi: 10.3892/etm.2015.2290

Figure 3.

Figure 3

Effect of EP on the expression levels of HMGB1, TNF-α and IL-6 in a rat myocardial ischemia/reperfusion model. The expression levels of HMGB1, TNF-α, IL-6 and GAPDH were analyzed in the sham, control, EP and EP + HMGB1 groups. The EP group was administered EP at 40 mg/kg, while the EP + HMGB1 group was administered EP at 40 mg/kg and rhHMGB1 at 100 μg/kg. Western blot bands were quantified by densitometry. EP, ethyl pyruvate; rhHMGB1, recombinant human high-mobility group box-1; TNF-α, tumor necrosis factor-α; IL-6, interlukin-6; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.