Table 2.

Effects of NPY on cti of immune cells

Cells	Sp	Specification	Rec	Effect / Chemoattractant	Age	Signal	Ref
Monocytes	H	Blood		↑ fetal calf serum			(Straub et al. 2000a)
Macrophages	M	Peritoneal resident cells (macrophages+lymphocytes)		↑ f-MLP	adult	PKC	(De la Fuente et al. 1993, De la Fuente et al. 2000, De la Fuente et al. 2001a)
Macrophages	M	Peritoneal resident cells (macrophages+lymphocytes)		↓ f-MLP	old		(De la Fuente et al. 2000, De la Fuente et al. 2001a)
Monocytes / Macrophages	M	RAW 264.7 cell line		↓ Leishmania major			(Ahmed et al. 1998)
Macrophages + Granulocytes	H			↓ f-MLP			(Dureus et al. 1993)
Monocytes + Granulocytes	R	Air pouch, LPS-elicited	Y1 + Y2	↓ migration to air pouch			(Mitic et al. 2011)
Granulocytes	R	Air pouch, carrageenan-elicited		↓ migration to air pouch			(Dimitrijevic et al. 2006, Dimitrijevic et al. 2010)
DCs	H	Blood	Y1	↑		ERK/MAPK	(Buttari et al. 2014)
Lymphocytes	M	Peritoneal resident cells (macrophages+lymphocytes) / axillary node leukocytes		↑ f-MLP	adult		(Medina et al. 1998b)
Lymphocytes	M	Thymus		↓ f-MLP			(Medina et al. 1998b)
Leukocytes	M	Peritoneal, spleen, thymus, axillary node		↑ axillary node, peritoneal, f-MLP			(Medina et al. 2000b)
Leukocytes	M	Peritoneal, spleen, thymus, axillary node		↓ thymus, f-MLP			(Medina et al. 2000b)

Abbreviations: DCs, dendritic cells; ERK, extracellular signal regulated kinases; f-MLP, N-formyl-methionyl-leucyl-phenylalanine; H, human; LPS, lipopolysaccharide; M, mouse; MAPK, mitogen-activated protein kinases; PKC, protein kinase C; R, rat; Rec, receptor; Sp, species.