Table 3.

Effects of NPY on phagocytosis of immune cells

Cells	Sp	Specification	Rec	Effect / Activating agent	Age	Signal	Ref
Macrophages	M	Peritoneal resident cells (macrophages+lymphocytes)		↑ latex beads, Candida albicans	adult	PKC	(De la Fuente et al. 1993, De la Fuente et al. 2000, De la Fuente et al. 2001a)
Macrophages	M	Peritoneal resident cells (macrophages+lymphocytes)		↓ latex beads	old		(De la Fuente et al. 2000, De la Fuente et al. 2001a)
Macrophages	M	Purified peritoneal		↓ latex beads	adult		(De la Fuente et al. 2001a)
Macrophages	M	Purified peritoneal		↑ latex beads	old		(De la Fuente et al. 2001a)
Monocytes / Macrophages	M	RAW 264.7 cell line		↓ Leishmania major			(Ahmed et al. 2001)
Monocytes / Macrophages	M	RAW 264.7 cell line		↓ unopsonized E. coli + Staph. aureus			(Phan & Taylor 2013)
Monocytes / Macrophages	M	RAW 264.7 cell line		↓ phagolysosome activation			(Phan & Taylor 2013)
Monocytes + Granulocytes	R	Blood	Y1	↑ zymosan			(Mitic et al. 2011)
Monocytes + Granulocytes	R	Air pouch, LPS-elicited	Y1+Y2	↓ zymosan			(Mitic et al. 2011)
Granulocytes	R	Air pouch, carrageenan-elicited	Y1	↓ zymosan	adult		(Dimitrijevic et al. 2006, Dimitrijevic et al. 2010)
Neutrophils	H	Blood		↑ E. coli (low dose)			(Bedoui et al. 2008)
Neutrophils	H	Blood	Y1+Y2	↓ E. coli (high dose)			(Bedoui et al. 2008)

Abbreviations: H, human; LPS, lipopolysaccharide; M, mouse; PKC, protein kinase C; R, rat; Rec, receptor; Sp, species.