Fig. 7.

The effects of acute and chronic salsolinol administration on the α-synuclein level in the substantia nigra, a 3 h and b 24 h withdrawal. Salsolinol was administrated acute or chronic at dose 100 mg/kg i.p. during 14 consecutive days. The control group was treated with saline. The rats were decapitated 3 or 24 h after last injection, respectively. The results are expressed as the mean ± SEM of six samples (n = 6 animals per group). Data were analyzed by means of one-way ANOVA followed by Tukey test. Statistical significance: *P < 0.05; **P < 0.01 versus control group