Fig. 7.

Effects of cocaine self-administration (a) and extinction training (b) on the mGluR₅, Homer1b/1c, and NMDA (subunits: NR1, NR2A, NR2B) receptor protein expression in the rat nucleus accumbens with a “yoked” control procedure. Data were normalized to saline-treated animals (% of yoked saline; YS) and represent the mean (±SEM) of 8–10 animals/group. **p < 0.01, ***p < 0.001 versus YS; ^ϕp < 0.05 versus YC. On the right, representative immunoblots for the protein levels of mGluR₅, Homer1b/1c, NR1, NR2A, and NR2B are shown