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. 2015 Feb 10;7(2):559–589. doi: 10.3390/v7020559

Figure 9.

Figure 9

Plasminogen activator inhibitor 1 (PAI-1) is highly upregulated in Class III HCPS patients as measured with ELISA assays. (A) Average expression of PAI-1 samples from individual control, cntrl (n = 5), Class I (n = 5), II (n = 5), and III (n = 4) subjects. Data show, analysis results of samples collected on day of admission to UNMH. Error bars reflect subject-to-subject variability with median, upper and lower limits as follows: cntrl (19.1, 29.8, 12.6); I (17.6, 25.4, 14.1); II (82.8, 120.3, 55.8); III (230.5, 1377.0, 59.0); (B) Plot of active PAI-1 expression in individual class III subjects identified as 281, 260, 256 and 280. Sample collection ended on different days due to death of the subjects. Error bars are duplicate measurements; (C) Plot of fold increase in active PAI-1 measured in pooled samples of Class II and individual Class III HCPS patients versus length of hospital stay (LOS). Error bars are duplicate measurements.