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Efficiency of Murine norovirus inactivation by formaldehyde at different temperatures. Virus titer was determined by TCID50 assay.
| Treatment | Temperature (°C) | Incubation Time (h) | Virus Titer (log10 TCID50/mL) |
|---|---|---|---|
| - | 4 | 1 | 7.2 |
| 2% FA | 4 | 1 | 4.4 |
| 2% FA | 4 | 1 | 4 |
| - | 25 | 1 | 7.6 |
| 2% FA | 25 | 1 | no CPE |
| 2% FA | 25 | 1 | no CPE |
| - | 25/37 | 0.5/0.5 | 7.4 |
| 2% FA | 25/37 | 0.5/0.5 | no CPE |
| 2% FA | 25/37 | 0.5/0.5 | no CPE |
CPE = cytopathic effect; Neutralization and toxicity tests performed as expected.
