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. 2015 Jan 6;6:5849. doi: 10.1038/ncomms6849

Figure 2. Tethered Rad4 opens up undamaged DNA nucleotide pairs as it does to damaged ones.

Figure 2

(a) Superposition of the Rad4–undamaged DNA (green-silver, this study) and the Rad4-damaged DNA8 (red-gold, PDB code 2QSH) structures. The crosslinked G* in DNA and Cys131 in Rad4 are indicated in purple and the flipped-out nucleotides are indicated in black in the undamaged DNA-bound structure. (b) Rad4-bound DNA conformations are nearly identical between the damaged- and the undamaged-bound conformations. Cytidines are represented in yellow boxes, thymidines in blue, guanosines in green and adenosines in red. The figure is generated by 3DNA44.