Table 1.
Common Acronyms and Terms With Their Descriptions
|
Acronyms/Terms |
Full Name/Description |
| ALI | Anterior LC insertion (Supplementary Fig. S1) |
| ANOVA | Analysis of variance |
| ASAS | Anterior-most subarachnoid space—the anterior-most extent of the CSF space defined by the dural insertion into the episcleral tissues |
| ASCO | Anterior scleral canal opening |
| BD | Beam diameter (Fig. 4) |
| BM | Bruch's membrane |
| BMO | Bruch's membrane opening |
| CSF | Cerebrospinal fluid |
| CTV | Connective tissue volume—in this study the sum of all connective tissue voxels |
| CTVF | Connective tissue volume fraction—in this study the ratio of CTV to LV expressed without units |
| EG | Experimental glaucoma |
| EO | Embedded orientation—the vertical and horizontal axes of the embedded ONH tissues within the 3D HMRN |
| FoBMO | Foveal–BMOcentroid |
| FoBMO axis | For 3D HMRN—a line connecting the estimated center of the fovea in a fundus image and the colocalized 3D HMRN BMOcentroid (Fig. 2) |
| FoBMO oriented | Using the FoBMO axis as the nasal-temporal midline for ONH 3D HMRN 30° sectoral regionalization (Fig. 1) |
| GEEGLM | A general linear model fitted with a generalized estimation equation |
| Global data | Lamina cribrosa data for a single ONH that includes all sectors, subsectors, and depths |
| HMRN | Histomorphometric reconstruction—stacked, serial digital section images from the stained embedded tissue block surface |
| ILM | Internal limiting membrane |
| LC | Lamina cribrosa |
| LMA | LC microarchitecture—in this study characterized by BD, PD, and CTVF |
| LV | Lamina cribrosa volume—in this study the sum of all beam and pore voxels |
| NB | Neural boundary—the boundary that contains the RGC axons as they pass through the wall of the eye (i.e., from BMO through the PSCO) |
| OD | Right eye |
| OD configuration | All data from both right and left eyes are presented in right eye configuration (Fig. 6) |
| ONH | Optic nerve head |
| OS | Left eye |
| Overall data | Lamina cribrosa data for all 21 eyes considered together |
| PD | Pore diameter (Fig. 4) |
| PSCO | Posterior scleral canal opening |
| RNFL | Retinal nerve fiber layer |
| SD | Standard deviation of the mean |
| SDOCT | Spectral-domain optical coherence tomography |