Table 3.
Post hoc sequence analysis of total and differential cell count in BAL
| Sequence (A): 1 st Period: UFP – 2 nd Period: Filtered air | |||||
| BAL Cells [106] | UFP mean (allergen-saline) | Filtered air mean (allergen-saline) | Treatment effect (UFP-FA) | 95%-confidence interval | p-value |
| Total cells | 13.4 | 75.1 | −61.6 | −110.4; −12.8 | 0.021 |
| Eosinophils | 13.2 | 64.1 | −50.9 | −95.5; −6.3 | 0.031 |
| Monocytes | 0.9 | 5.7 | −4.8 | −8.3; −1.4 | 0.013 |
| Macrophages | 0.3 | 6.9 | −6.6 | −18.7; 5.5 | 0.232 |
| Neutrophils | −0.8 | 1.9 | −2.7 | −7.6; 2.1 | 0.219 |
| Lymphocytes | 0.0 | 1.0 | −1.0 | −3.1; 1.2 | 0.313 |
| Sequence (B): 1 st Period: Filtered air – 2 nd Period: UFP | |||||
| BAL Cells [106] | Filtered air mean (allergen-saline) | UFP mean (allergen-saline) | Treatment effect (UFP-FA) | 95%-confidence interval | p-value |
| Total cells | 4.5 | 29.3 | 24.8 | −33.2; 82.8 | 0.300 |
| Eosinophils | 3.7 | 26.1 | 22.5 | −25.5; 70.4 | 0.263 |
| Monocytes | 0.4 | 3.5 | 3.2 | −5.7; 12.0 | 0.377 |
| Macrophages | 0.6 | 0.7 | 0.1 | −5.8; 6.0 | 0.951 |
| Neutrophils | 0.2 | 1.1 | 0.8 | −2.2; 3.8 | 0.492 |
| Lymphocytes | −0.1 | 0.6 | 0.6 | −1.9; 3.2 | 0.531 |