Table 3.
Summary of significant regions from Map 1.
Region | X | Y | Z | Volume | Regression vs. CARE | Regression vs. BIS | F-test | |||
---|---|---|---|---|---|---|---|---|---|---|
(mm) | (mm3) | P | T | P | T | P | F | |||
From Map 1: Response Inhibition Contrast vs CARE Scores with CARE > BIS | F-test CARE > BIS | |||||||||
Right OFC | 27.0 | 26.0 | −20.0 | 3537 | 0.0155 | −2.46 | 0.1334 | −1.51 | <0.0001 | 19.05 |
vmPFC | 9.0 | 47.0 | −11.0 | 4158 | 0.0192 | −2.38 | 0.4458 | −0.77 | <0.0001 | 28.42 |
Right occipital | 33.0 | −85.0 | 22.0 | 4401 | 0.0261 | 2.26 | 0.3170 | 1.01 | <0.0001 | 22.75 |
Summary of significant regions from Map 1: comparison of fMRI response inhibition contrast (NoGo—Go) vs. CARE risk scores where CARE scores also accounted for significantly more variance than BIS scores. Statistical comparison of inhibition contrast vs. BIS impulsivity scores (Map 2) did not yield any significant regions. X, Y, Z: MNI coordinates of region's peak statistical voxel. P- and t-values are median values across all voxels in a region (df = 98). Positive and negative t-values indicate, respectively, greater and lesser inhibition contrast values for participants with larger CARE scores. F-test CARE > BIS are median values across each region from the F-map testing whether CARE scores accounted for significantly more variance in response inhibition contrast values than BIS scores (df = 1, 97). See Section 2.7 for analysis details. OFC: orbitofrontal cortex. vmPFC: bilateral ventromedial prefrontal cortex. Occipital: occipital cortex.