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. 2015 Mar 17;5(3):e527. doi: 10.1038/tp.2014.141

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Copyright © 2015 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Expression of putative molecular markers of stem cells, neural progenitors, neurons and glia by various olfactory mucosa (OM) cell types, both in adult OM in vivo and in cells generated from adult OM tissues in vitro. Studies of OM explant tissues or dissociated cells immediately ex vivo are not included. Percentage values are approximate, and refer to the proportion of cells in culture which express each marker. Values are only shown for markers displaying consistency between studies, and only for cells grown in serum-containing media. *, studies using neonatally-derived rodent or fetally-derived human ON culture cells; ^&, markers whose significance in OM culture cells is uncertain due to a discordance between human and rodent (for example, p75NGFR), low/uncertain levels of expression in adult ON in vivo (NF-M/H, Nestin, NeuN, MAP2) or a possible lack of cell type specificity (p75NGFR, Vimentin); ^#, markers whose expression increase when cells are cultured in base (unsupplemented defined) media rather than serum-containing media; ^, mesenchymal stem cell cluster of differentiation (MSC-CD) markers, used to confirm cell type, vary among studies. CK, cytokeratin; INP, intermediate neural progenitor; LP, lamina propria (indicates cultures derived solely from LP, without ON); LP-MSC, lamina propria mesenchymal stem cell; ND, not detected; NTR, neurotransmitter receptor; OEC, olfactory ensheathing cell; ON, olfactory neuroepithelium; OSN, olfactory sensory neuron.