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. 2015 Mar 10;3:28. doi: 10.3389/fbioe.2015.00028

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Copyright © 2015 Manconi, Manca, Moscatelli, Gnocchi, Orro, Armano and Milanesi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The RD in a genomic region depends on the copy number of that region and follows a Poisson distribution. Duplicated and deleted regions are characterized by a RD signal different from that of the other ones.