TABLE 3.
Comparison of methylation within a locus between sexes, separately in FAS and controls.
| Locus | Group | Effect | SE | P-value |
|---|---|---|---|---|
| H19 ICR | CON | 0.33 | 0.48 | 0.495 |
| H19 ICR | FAS | –0.16 | 0.40 | 0.687 |
| IG-DMR1.A | CON | 0.37 | 0.46 | 0.428 |
| IG-DMR1.A | FAS | 0.18 | 0.38 | 0.626 |
| IG-DMR1.B | CON | –0.45 | 0.46 | 0.329 |
| IG-DMR1.B | FAS | –0.60 | 0.38 | 0.112 |
| KvDMR1 | CON | 0.10 | 0.39 | 0.795 |
| KvDMR1 | FAS | –0.22 | 0.32 | 0.490 |
| PEG3 DMR | CON | –0.84 | 0.41 | 0.042 |
| PEG3 DMR | FAS | 1.11 | 0.33 | 0.001 |
CON, controls; FAS, FAS case; Effect, the estimated percentage difference in methylation between males and females in the specific group at the specific locus, using linear mixed-effects models, as described in methods section; SE, standard error of the effect estimate. Significant: p < 0.05. Analyses are adjusted for variation between sites and also for variation between individuals and within individuals as random effects.